Infection Biomarker Discovery

Uncovering early infection and vaccine efficacy

During very early stages of microbial infections, a series of physiological and molecular changes including differential gene expression, proteomic and metabolomic interactions occur in the host. Orion Integrated Biosciences has the technology to measure and correlate this information and to understand the complex molecular interactions that take place during pathogenesis and disease. These systems biology applications can uncover early infection biomarkers capable of discriminating healthy from disease states produced by different pathogens, or help predict drug response and disease prognosis, or monitor treatment with a given prophylactic product. This information can be used to identify immune-regulatory interactions that can be targeted with specific small molecules.